Comedian Nikki Glaser didn't hold back during her Golden Globes hosting gig, delivering a monologue filled with pointed jokes about celebrities like Sean "Diddy" Combs and Ben Affleck. Held at the Beverly Hilton, the evening began with Glaser playfully referring to the event as "Ozempic's biggest night," a reference to the popular weight-loss drug.

Glaser praised Zendaya's performance in the sexually charged tennis drama "Challengers," comparing the film's heat to "Diddy's credit card." She quipped about the potential impact on the after-party, given the legal issues surrounding Diddy, whose homes were raided in connection with a human trafficking investigation. The raid reportedly uncovered a large quantity of baby oil and lubricant, among other items.

Glaser also took aim at Ben Affleck, currently going through a divorce from Jennifer Lopez. She joked about the titles of nominated films like "Wicked," "Queer," and "Nightbitch," suggesting they resembled Affleck's exclamations during intimate moments.

Before the event, Glaser reflected on her 22-year journey in the entertainment industry, starting with "Last Comic Standing" and progressing through shows on MTV and Comedy Central. She credited former Golden Globes host Ricky Gervais with offering valuable advice, reassuring her that she would excel because she wasn't "one of them."